Cleanroom service

When it comes to cleaning, decontaminating and disinfecting cleanrooms and process equipment in particular, expertise and a high level of awareness of your own impact on the production environment are what count. Qualified and experienced comprei employees decontaminate over 200 cleanrooms and machines every day. This includes pharmaceutical and microtechnical equipment (EU-GMP, ISO14644). The service is performed in a traceable and documented manner in accordance with SOPs.

Optionally, we can work with the customer to adapt the cleaning processes to improve quality by means of process analysis and risk assessment. If your cleanrooms require unscheduled special cleaning at short notice, we guarantee the prompt deployment of a comprei team.

Technical cleanrooms / particle-controlled
GMP / particulate and microbiologically controlled

Technical cleanrooms / particle-controlled

Various types of contamination play a key role in the production of sensitive high-tech components and parts. The degree of cleanliness of the production environment and all materials/equipment used are directly related to the cleanliness of the manufacturing processes and the end product at all times.

comprei offers these cleanroom services:

Installation, assembly/dismantling, cleaning and decontamination/preparation, packaging, removal of highly sensitive equipment and machines in the semiconductor sector by experienced specialists. These include mechanics, electricians, mechatronics engineers and fitters qualified for cleanrooms. To ensure occupational safety, these teams are trained in handling chemicals and acids.
Maintenance cleaning - the ongoing, regularly recurring cleaning of production cleanrooms by sensitized cleanroom cleaning staff.
Special cleaning - preparation before qualification and requalification of cleanrooms and after technical maintenance work such as production stops, filter replacements, conversions, unforeseen events such as fire or flooding.
Cleanroom-compatible packaging concepts

GMP / particulate and microbiologically controlled

The manufacture of medicinal products is subject to strict regulations and hygiene standards. In particular, the revision of the GMP guidelines, Annex 1, focuses on the establishment and implementation of a Contamination Control Strategy (CCS) for manufacturers of sterile medicinal products as well as non-sterile forms. The professional cleaning and disinfection of the production environment in accordance with written programs is an essential part of this strategy.

comprei offers these cleanroom services:

Maintenance cleaning - the continuous cleaning and disinfection of production and laboratory rooms by sensitized cleanroom cleaning staff.
Optionally, we can work with you to adapt the cleaning processes to improve quality by means of process analysis and risk assessment. This includes the selection of suitable cleaning agents and disinfectants as well as the definition of suitable procedures.
Special cleaning before qualification and requalification of cleanrooms and after shutdowns

Technical maintenance work (filter replacement, conversions, etc.)
after unforeseen events such as fire, flooding, etc.
in the event of microbiological deviations
when commissioning new lines (plants for aseptic filling of medicines, sterile areas of hospital pharmacies and compounding centers...)

The concept of special cleaning is always developed together with you after analyzing the initial situation (incl. inspection) and precisely defining the target condition.

Personnel qualification

After completing onboarding, every member of our service team is included in the ongoing qualification program. This program ensures that the necessary professional competence, awareness and skills are available at all times.(Training in accordance with ISO 21001 and ISO 29993 standards)

Employees of our service teams benefit from the same quality of training that renowned companies purchase from us.

The focus of continuous qualification is on

Recognizing contamination potential
Methods for avoiding contamination
Awareness of critical work areas
Knowledge and understanding of the relevant standards (ISO 14644, VDI 2083, GMP guidelines)
Cleaning and disinfection techniques for cleanrooms and controlled areas
Suitable wiping techniques for different surfaces
Special features of room cleaning (ceiling, walls, floor)
Handling of cleanroom cleaning equipment
Simulation of typical situations and finding solutions
Visualization of contamination and its carryover

The service is performed and documented in accordance with the operator's standard operating procedures (SOPs). If these are not yet available, the internal comprei standard documents are used.

comprei personnel

Even when selecting employees, comprei's management pays great attention to accuracy, reliability, flexibility, honesty, friendliness and linguistic understanding with regard to documentation and work instructions. We are very aware of the direct link between customer satisfaction and employee satisfaction. For this reason, comprei invests specifically in employee satisfaction.

The result for you:

High continuity, as there is hardly any staff turnover
Continuous and reproducible results, even in the case of replacement personnel
Reduced effort for monitoring the service, as comprei employees work exclusively in the cleanroom = "cleanroom self-image".